[Scanning electron microscopic observation on odontogenic keratocysts]

Area of Science:

• Oral pathology
• Scanning electron microscopy
• Epithelial cell biology

Context:

• Odontogenic keratocysts (OKCs) are common developmental cysts with a high recurrence rate.
• Understanding the ultrastructure of OKC epithelial lining is crucial for diagnosis and management.
• Previous studies have provided limited information on the three-dimensional ultrastructure of OKC epithelial cells.

Purpose:

• To investigate the three-dimensional ultrastructure of the epithelial lining cells of odontogenic keratocysts using scanning electron microscopy (SEM).

Summary:

• Scanning electron microscopy (SEM) was used to examine five odontogenic keratocysts.
• The study revealed a stratified epithelial lining with a basal layer of columnar/cuboidal cells, a spinous cell layer, and a superficial parakeratinized layer.
• High-magnification SEM imaging showed microvilli and branched/anastomosing microridges on the superficial cell surfaces.

Impact:

• Provides detailed ultrastructural insights into odontogenic keratocyst epithelial lining.
• May contribute to a better understanding of OKC behavior and pathogenesis.
• Highlights the utility of SEM in characterizing oral cystic lesions.