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Behcet's disease and cardiovascular involvement: our experience of asymptomatic Behcet's patients
Zeynep Ulusan1, Ayse Serap Karadag2, Mehmet Tasar3
1Kecioren Research and Training Hospital, Ankara, Turkey. uusanzeynep@hotmail.com.
Insights
Behcet
Area of Science:
- Rheumatology
- Cardiology
- Vascular Medicine
Background:
- Behcet's syndrome is a systemic inflammatory condition.
- It is characterized by vasculitis affecting various organs.
- Cardiovascular complications are a significant concern in Behcet's disease.
Purpose of the Study:
- To prospectively evaluate cardiovascular involvement in Behcet's disease patients.
- To identify the prevalence of arterial, venous, and cardiac abnormalities.
- To assess coagulation parameters in these patients.
Main Methods:
- Echocardiography, ultrasonography, and computed tomography were utilized.
- Coagulation parameters were systematically determined.
- Thirty-eight patients diagnosed with Behcet's disease were included.
Main Results:
- Deep venous insufficiency (16 patients) and venous thrombosis (7 patients) were common.
- Arterial involvement included iliac artery stenosis (1 patient) and carotid intimal proliferation (3 patients).
- Cardiac findings comprised aortic annulus dilatation (2 patients), aortic valve insufficiency (6 patients), and mitral valve insufficiency (3 patients). No coagulation defects were observed.
Conclusions:
- Cardiovascular manifestations are prevalent in Behcet's disease.
- Early diagnosis and management of cardiac and vascular issues are crucial.
- A multidisciplinary approach is vital for improving outcomes in Behcet's disease patients.
Abstract:
Behcet's syndrome is a systemic inflammatory disease associated with vasculitis, and arterial, venous and cardiac disorders. Thirty-eight Behcet's disease patients were examined prospectively with echocardiography, ultrasonography and computed tomography, and coagulation parameters were determined. Deep venous insufficiency was found in 16 patients, venous thrombosis in seven, one patient had iliac artery stenosis, three had carotid arterial intimal proliferation, two patients had aortic annulus dilatation, six had aortic valve insufficiency, and three had mitral valve insufficiency. None had coagulation defects. To decrease morbidity and mortality rates, a multidisciplinary approach is important for early diagnosis of cardiovascular involvement in Behcet's disease.