Genetic determinants of P wave duration and PR segment

Niek Verweij1, Irene Mateo Leach1, Malou van den Boogaard1

  • 1From the Department of Cardiology (N.V., I.M.L., D.J.v.V., H.L.H., W.H.v.G., R.A.d.B., P.v.d.H.) and Department of Genetics (P.v.d.H.), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Anatomy, Embryology and Physiology, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands (M.v.d.B., V.M.C., P.B.); and Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands (P.v.d.H.).

Summary

Genetic factors influencing the PR interval (ECG) primarily affect the PR segment, with some also impacting P wave duration. Novel genetic variants specifically linked to P wave duration were identified, offering insights into cardiac biology.

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