[Study of ADC value in healthy adults kidney of different age groups]

To evaluate the changes of ADC value on renal parenchyma at different age groups in healthy adults.

One hundred healthy adults were divided into five groups based on age:namely 18-29 years, 30-39 years, 40-49 years, 50-59 years and 60-69 years. All adults underwent diffusion-weighted magnetic resonance(MR) imaging of the kidneys with b values of 800 s/mm(2). ADC values of renal parenchyma were measured by the manufacturer's software.

With the increasing of age , the renal parenchyma ADCs decrease. The ADCs of renal parenchyma in five age groups were (2.07 ± 0.10) ×10(-3)mm(2)/s, (2.06 ± 0.12) ×10(-3)mm(2)/s, (2.03 ± 0.10) ×10(-3)mm(2)/s, (1.98 ± 0.17) ×10(-3)mm(2)/s and (1.94 ± 0.12) ×10(-3)mm(2)/s, which had statistically significant different (F = 3.375, P < 0.05).

(1)The ADCs of renal parenchyma may be influenced by age , with the increasing of age, ADCs of normal kidney presented tenuous decreasing tendency especially the people aged ≥ 40 years; (2)in clinical application, we ought to pay attention to the influence of age factor. Income data of this study can be took as normal reference value in other more study.