Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

4.6K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
4.6K
Motor Unit Stimulation01:20

Motor Unit Stimulation

4.7K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacokinetics of Fentanyl and Norfentanyl in a Rat Model of Fixed-Volume Hemorrhagic Shock.

European journal of drug metabolism and pharmacokinetics·2026
Same author

The Bachmann's bundle connection: from obesity and aging to atrial arrhythmia development.

Folia morphologica·2026
Same author

Impact of environmentally induced hypothermia on fentanyl and norfentanyl pharmacokinetics following intravenous administration to Wistar rats.

Pharmacological reports : PR·2026
Same author

Disturbances of autonomic nervous system and gastric activity in response to visceral stimulation in functional dyspepsia patients.

Przeglad gastroenterologiczny·2025
Same author

Dopa decarboxylase and angiotensin converting enzyme 2 immunoexpression in the gastrointestinal tract of control female Wistar rats - a pilot study.

Folia medica Cracoviensia·2025
Same author

Cobalamin Status Among Patients with Fetal Alcohol Spectrum Disorder (FASD)-A Preliminary Study.

Nutrients·2025

Related Experiment Video

Updated: Apr 29, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

31.9K

Is the vagus nerve stimulation a way to decrease body weight in humans?

Andrzej Bugajski1, Krzysztof Gil2

  • 1Department of Pathophysiology, Jagiellonian University Medical College, Krakow, Poland. andrzej.bugajski@uj.edu.pl.

Folia Medica Cracoviensia
|May 24, 2014
PubMed
Summary
This summary is machine-generated.

Manipulating the vagus nerve offers a promising new approach to obesity treatment. By influencing the central nervous system, this method targets energy homeostasis and food intake regulation.

More Related Videos

Author Spotlight: Exploring Abdominal VNS for Inflammatory Conditions
07:17

Author Spotlight: Exploring Abdominal VNS for Inflammatory Conditions

Published on: January 19, 2024

2.9K
Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations
06:31

Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations

Published on: January 7, 2019

42.9K

Related Experiment Videos

Last Updated: Apr 29, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

31.9K
Author Spotlight: Exploring Abdominal VNS for Inflammatory Conditions
07:17

Author Spotlight: Exploring Abdominal VNS for Inflammatory Conditions

Published on: January 19, 2024

2.9K
Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations
06:31

Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation taVNS: Technique, Targeting, and Considerations

Published on: January 7, 2019

42.9K

Area of Science:

  • Neuroscience
  • Metabolic Disorders
  • Gastroenterology

Background:

  • Obesity is a growing global health issue with limited treatment efficacy.
  • Current behavioral, pharmacological, and surgical options for obesity present challenges.
  • The vagus nerve plays a crucial role in regulating energy homeostasis and food intake.

Purpose of the Study:

  • To explore the potential of vagus nerve manipulation as an alternative obesity treatment.
  • To understand the neural pathways involved in regulating feeding behavior via the vagus nerve.

Main Methods:

  • Review of the role of the vagus nerve in afferent and efferent signaling.
  • Examination of the neural pathways from the vagus nerve to the hypothalamus.
  • Discussion of pharmacological or electrical manipulation of vagus nerve activity.

Main Results:

  • The vagus nerve transmits critical information to the brainstem and hypothalamus, influencing feeding behavior.
  • Afferent vagal fibers, particularly unmyelinated C-type fibers, are sensitive to electrical stimulation.
  • Efferent vagal stimulation impacts gastrointestinal motility and secretion.

Conclusions:

  • Vagus nerve manipulation, through stimulation or blocking, presents a potential therapeutic strategy for obesity.
  • Targeting the vagus nerve influences central nervous system regulation of energy balance.
  • This approach offers a novel alternative to existing obesity management strategies.