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Updated: Apr 29, 2026

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
Published on: December 16, 2022
Labelling Polymers and Micellar Nanoparticles via Initiation, Propagation and Termination with ROMP
Matthew P Thompson1, Lyndsay M Randolph1, Carrie R James1
1Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, CA, U.S.A.. Fax: XX XXXX XXXX; Tel: XX XXXX XXXX.
Abstract:
In this paper we compare and contrast three approaches for labelling polymers with functional groups via ring-opening metathesis polymerization (ROMP). We explored the incorporation of functionality via initiation, termination and propagation employing an array of novel initiators, termination agents and monomers. The goal was to allow the generation of selectively labelled and well-defined polymers that would in turn lead to the formation of labelled nanomaterials. Norbornene analogues, prepared as functionalized monomers for ROMP, included fluorescent dyes (rhodamine, fluorescein, EDANS, and coumarin), quenchers (DABCYL), conjugatable moieties (NHS esters, pentafluorophenyl esters), and protected amines. In addition, a set of symmetrical olefins for terminally labelling polymers, and for the generation of initiators in situ is described.
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