A rare case of silent transmural myocardial infarction with diffuse ST elevations complicated by concomitant severe
Mokhtar Abdallah1, Rehan Raza1, Tarek Abdallah2
1Department of Medicine, Staten Island University Hospital (SIUH), New York, USA.
Insights
Silent myocardial infarction (MI) can mimic hyperkalemia symptoms. High-risk patients require a high index of suspicion for accurate diagnosis and timely treatment to prevent mortality.
Area of Science:
- Cardiology
- Emergency Medicine
- Nephrology
Background:
- Silent myocardial infarction (MI) presents atypical symptoms in high-risk groups like diabetics.
- Electrocardiogram (EKG) ST elevations are key for Acute MI diagnosis in the ER.
- Hyperkalemia can cause diffuse ST elevations, mimicking MI and complicating diagnosis.
Observation:
- A 67-year-old female with diabetes and CKD presented with severe hyperkalemia and EKG ST elevations.
- The patient was asymptomatic, with no chest pain or distress.
- Cardiac catheterization revealed a totally occluded proximal left circumflex artery with a large thrombus.
Findings:
- The case highlights the diagnostic challenge of asymptomatic MI mimicking hyperkalemia.
- Despite hyperkalemia's pseudoinfarction pattern, acute MI must be ruled out urgently.
- Bedside echocardiography can exclude regional wall motion abnormalities, aiding diagnosis.
Implications:
- A high index of suspicion is crucial for diagnosing MI in high-risk, asymptomatic patients.
- Prompt diagnosis and intervention are critical for reducing mortality in acute MI.
- This case underscores the importance of considering MI even with confounding electrolyte disturbances.
Abstract:
It is well described that certain group of patients do not display the typical symptoms of myocardial infarction (MI). Elderly patients, diabetics and those with previous coronary artery bypass graft surgery are at high risk for silent MI. The diagnosis of Acute MI in the emergency room (ER) is mainly based on the electrocardiogram (EKG) findings of ST elevations or new onset left bundle branch block which is supported by the clinical presentation and positive biomarkers when present. The diagnoses can sometimes become challenging when the patient is asymptomatic and has coincidental finding of hyperkalemia with diffuse ST segment elevations simulating that seen with electrolyte disturbance. Despite the well known pseudoinfarction pattern of hyperkalemia, acute MI should be ruled out first. A high index of suspicion is needed, especially in high risk patients. We think that in rare clinical situation when the diagnosis is in doubt, MI should be ruled out, as time has a high impact on patient mortality. An urgent bedside echocardiogram is very beneficial in excluding regional wall motion abnormalities and preventing any delay in destination therapy for transmural MI. We present a 67 years old female with history of diabetes and chronic kidney disease sent by her nephrologist to the ER for severe hyperkalemia (Potassium 7.2 milliequivalent/L). She was found to have ST elevations on EKG despite having no chest pain or distress. On cardiac catheterization she had a total occlusion of the proximal left circumflex artery, with a filling defect consistent with large thrombus.
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