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Updated: Apr 29, 2026
Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
MM-MTA for direct pulp capping: a histologic comparison with ProRoot MTA in rat molars
Issam Tanios Khalil1, Tony Sarkis2, Alfred Naaman3
1Assistant Professor, Department of Endodontics, Saint Joseph University, Lebanon,
Aim:
To compare the histomorphological response of rat dental pulps capped with MM-MTA and ProRoot MTA at 1, 2 and 4 weeks postoperatively.
Materials And Methods:
Direct pulp capping with MM-MTA and ProRoot MTA, overlaid with light-cured composite resin, was performed on right and left maxillary first molars of 20 Wistar rats. Animals were killed at 1, 2 and 4 weeks postoperatively. Biopsy samples were stained and viewed by light microscopy to determine dentin bridge formation. Data were statistically evaluated with the Kruskal-Wallis test (p < 0.05).
Results:
Absence of dentin bridge formation at 1 week, partial dentin bridge formation at 2 weeks and complete dentin bridge formation at 4 weeks are observed with MM-MTA and ProRoot MTA. The results showed no statistically significant difference between both materials at 4 weeks.
Conclusion:
Both materials produced similar responses in the pulp when used for pulp capping in intact, caries-free molars of rats.
