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Management of choroid plexus tumors in children
1George Washington University, Children's National Medical Center, Washington, D.C.
Insights
Choroid plexus tumors are a common pediatric cancer, often large at diagnosis. Complete surgical removal is the primary treatment, though challenges like hydrocephalus may require cerebrospinal fluid diversion.
Area of Science:
- Pediatric Neurosurgery
- Pediatric Oncology
- Neuro-oncology
Background:
- Choroid plexus tumors are a significant cause of pediatric brain tumors.
- These tumors are frequently diagnosed in infants and present at a large size.
Purpose of the Study:
- To discuss the challenges and management strategies for pediatric choroid plexus tumors.
- To review operative approaches and alternative treatments for these challenging tumors.
Main Methods:
- Review of surgical techniques for tumor resection.
- Discussion of management for associated hydrocephalus.
- Exploration of adjuvant treatment options.
Main Results:
- Total tumor resection is the preferred treatment modality.
- Hydrocephalus requiring cerebrospinal fluid diversion is common.
- Tumor size and hydrocephalus pose significant surgical challenges.
Conclusions:
- Effective management of pediatric choroid plexus tumors requires addressing both the tumor burden and associated hydrocephalus.
- Pediatric neurosurgeons face considerable challenges due to tumor size and complexity.
- Comprehensive treatment strategies are essential for optimal patient outcomes.
Abstract:
Choroid plexus tumors are most common in the first year of life and are quite large at presentation. Total resection is the treatment of choice, and many children require diversion of the cerebrospinal fluid despite removal of the tumor. Tumor size and associated hydrocephalus present formidable challenges to the pediatric neurosurgeon. The operative approaches as well as other treatment options are discussed.