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A controlled study of serum lipid profiles in Indian patients with depressive episode
Bichitra Nanda Patra1, Sudhir K Khandelwal1, Rakesh K Chadda1
1Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Background:
Lower levels of circulating lipid fractions and cholesterol are risk factors for impulsivity and depressive disorder. A lower level of serum cholesterol is also associated with patients presenting with history of self-harm.
Materials And Methods:
A total of 30 depressive patients and 30 healthy matched control subjects were recruited from the department of Psychiatry of a tertiary care hospital. We measured serum total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein cholesterol and triglyceride levels of both patient and control group.
Results:
The serum TC and LDL-cholesterol levels were found to be significantly lower in study group than that of control group.
Conclusion:
Lower levels of serum cholesterol are associated with depressive disorder.
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