Hypomelanosis of ito: histochemical and ultrastructural observations

Skin biopsies were taken from an infant girl with Hypomelanosis of Ito (Incontinentia Pigmenti Achromians) for histopathological, histochemical and electron microscopic studies. Histological observations were similar to those reported previously. Electron microscopy revealed two groups of melanocytes, an effete group and another group with a highly dendritic appearance. The significance of these findings is discussed.