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Sympathetic skin response in patients with vascular erectile dysfunction
Mostafa Jazayeri1, Behrooz Kazemi1, Alireza Aminsharifi2
1Department of Physical Medicine and Rehabilitation, Shiraz University of Medical Sciences, Shiraz, Iran.
The World Journal of Men'S Health
|May 30, 2014
Summary
The sympathetic skin response (SSR) test effectively identifies autonomic dysfunction in men with vasculogenic erectile dysfunction (ED). Abnormal SSR results correlate with more severe ED, suggesting its utility in assessing this common impotence type.
Area of Science:
- Urology
- Neurology
- Cardiology
Background:
- Vasculogenic erectile dysfunction (ED) is the most common form of impotence.
- Autonomic dysfunction can contribute to vasculogenic ED.
- The sympathetic skin response (SSR) test assesses autonomic nervous system function.
Purpose of the Study:
- To evaluate the diagnostic utility of the SSR test in men with vasculogenic ED.
- To determine the correlation between SSR test results and ED severity.
- To explore the relationship between SSR findings and comorbidities.
Main Methods:
- Recruited 42 men aged 28-60 with confirmed vasculogenic ED.
- Assessed ED severity using the International Index of Erectile Function (IIEF-5).
- Recorded SSR from penile nerves (median, tibial, dorsal) and analyzed data using statistical tests (ANOVA, t-test, Pearson's correlation, Mann-Whitney U, Kruskal-Wallis).
Main Results:
- A strong statistical relationship was found between IIEF scores and abnormal SSR.
- Patients with abnormal SSR exhibited more severe ED (p<0.001).
- ED severity also correlated significantly with diabetes mellitus and cardiovascular disease (p<0.05).
Conclusions:
- The SSR test confirms autonomic dysfunction in patients with vasculogenic impotence.
- SSR testing shows potential for monitoring treatment response in vascular impotence.
- Further studies are recommended to validate SSR efficacy in treatment response assessment.
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