Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Challenge provocation tests and non-specific bronchial hyperactivity in occupational asthma].

S Balland, M Grosclaude, E Jarsaillon

    Journal De Toxicologie Clinique Et Experimentale
    |January 1, 1989
    PubMed
    Summary

    Realistic challenge tests for nasal and bronchial symptoms show high positivity rates in occupational respiratory cases. A strong correlation exists between these realistic tests and non-specific bronchial hyperreactivity (BHR).

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Mandibular advancement device and multidisciplinary consultation of sleep-disorders].

    Revue des maladies respiratoires·2021
    Same author

    Benefit of continuous positive airway pressure on work quality in patients with severe obstructive sleep apnea.

    Sleep & breathing = Schlaf & Atmung·2019
    Same author

    In vivo clinical and radiological effects of platelet-rich plasma on interstitial supraspinatus lesion: Case series.

    Orthopaedics & traumatology, surgery & research : OTSR·2017
    Same author

    [Genetic and environmental factors of asthma and allergy: Results of the EGEA study].

    Revue des maladies respiratoires·2015
    Same author

    Teres major muscle tear in two professional ice hockey players: cases study and literature review.

    Orthopaedics & traumatology, surgery & research : OTSR·2011
    Same author

    [Treatment of tendinopathies: role for autologous platelet-rich plasma injections].

    Revue medicale suisse·2011

    Area of Science:

    • Occupational Medicine
    • Allergy and Immunology
    • Pulmonology

    Background:

    • Occupational respiratory symptoms are common and can significantly impact worker health.
    • Accurate diagnosis of occupational asthma and rhinitis is crucial for effective management.
    • Existing diagnostic methods may not fully capture the impact of workplace exposures.

    Purpose of the Study:

    • To evaluate the diagnostic utility of realistic challenge tests for nasal and bronchial symptoms in an occupational setting.
    • To determine the correlation between realistic challenge test results and non-specific bronchial hyperreactivity (BHR).

    Main Methods:

    • A study involving 75 patients with suspected occupational respiratory symptoms.
    • Included allergy skin prick tests, total and specific IgE measurements, spirometry, and methacholine challenge tests for BHR.

    Related Experiment Videos

  • Realistic challenge tests using rhinomanometry and plethysmography to measure nasal resistance (NR) and airway resistance (RWA).
  • A positive test was defined as a 100% increase in RWA and/or NR.

    • Main Results:

    • 68% of realistic challenge tests (rhinomanometry and/or plethysmography) were positive.
    • Bronchial hyperreactivity (BHR) was present in 68% of occupational asthma cases.
    • A strong correlation was observed between positive realistic challenge tests and the presence of non-specific BHR.

    Conclusions:

    • Realistic challenge tests are valuable tools for diagnosing occupational respiratory symptoms.
    • These tests show a significant correlation with non-specific bronchial hyperreactivity.
    • Integrating realistic challenge tests can improve the diagnosis and management of occupational respiratory diseases.