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Tattoo-associated uveitis.

Trucian A Ostheimer1, Bryn M Burkholder1, Theresa G Leung1

  • 1Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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|May 31, 2014
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Summary
This summary is machine-generated.

Skin tattoos may trigger immune responses, causing simultaneous eye (uveitis) and skin inflammation. This case series describes seven patients experiencing coincident uveitis and raised, indurated tattoos, highlighting a potential link between tattooing and inflammatory conditions.

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Immunology

Background:

  • Uveitis is intraocular inflammation.
  • Tattooing involves injecting ink into the dermis.
  • Immune responses to tattoo ink are possible.

Purpose of the Study:

  • To describe clinical presentation of uveitis.
  • To investigate coincident raised and indurated tattooed skin.

Main Methods:

  • Case series of seven patients.
  • Ophthalmic examination and systemic evaluation.
  • Tattoo biopsy in two patients.

Main Results:

  • Five patients had anterior uveitis; two had panuveitis.
  • Tattoo biopsies showed granulomatous inflammation around ink.
  • Skin and eye inflammation resolved with prednisone; recurrences noted.

Conclusions:

  • Skin tattooing may incite immune responses.
  • This can lead to simultaneous eye and tattooed skin inflammation.
  • Represents a subset of patients with tattoo-associated inflammatory conditions.