Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Data Validation01:15

Data Validation

3.7K
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
3.7K
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

14
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated...
14
Testing a Claim about Standard Deviation01:19

Testing a Claim about Standard Deviation

2.1K
A complete procedure to test a claim about population standard deviation or population variance is explained here.
The hypothesis testing for the claim of population standard deviation (or variance) requires the data and samples to be random and unbiased. The population distribution also must be normal. There is no specific requirement on the sample size as the estimation is based on the chi-square distribution.
As a first step, the hypothesis (null and alternative) concerning the claim about...
2.1K
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

1.6K
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
1.6K
Hyperglycemia01:29

Hyperglycemia

24
Hyperglycemia is an abnormally high blood glucose level. It is diagnosed by fasting glucose ≥126 mg/dL, 2-hour oral glucose tolerance test (or OGTT) ≥200 mg/dL, random glucose ≥200 mg/dL with symptoms, or HbA1c ≥6.5%. However, HbA1c results may be unreliable in certain conditions, such as anemia or hemoglobinopathies, and the diagnosis should be confirmed unless classic symptoms are present. Postprandial hyperglycemia is typically considered significant when glucose...
24
Instrument Calibration01:12

Instrument Calibration

1.4K
Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Detection of Down Syndrome Arthritis in Clinical Practice: A Multicenter, International Pilot and Feasibility Study of a Down Syndrome-Specific Musculoskeletal Screening Tool.

American journal of medical genetics. Part A·2025
Same author

Botulinum Toxin: Surely, We Can Do Better? Optimizing Results Beyond On-Label Techniques and Teaching.

Aesthetic surgery journal. Open forum·2025
Same author

Response to: Hyaluronidase Availability Beyond the Aesthetic Office: A Shared Responsibility for Safety in Filler Complications.

Aesthetic surgery journal·2025
Same author

Quality Improvement to Identify and Address Food Insecurity During Pediatric Hospitalizations.

Hospital pediatrics·2024
Same author

The Development of a Pediatric Catatonia Clinical Roadmap for Clinical Care at Vanderbilt University Medical Center.

Journal of the Academy of Consultation-Liaison Psychiatry·2024
Same author

Factors limiting the potential range expansion of lodgepole pine in Interior Alaska.

Ecological applications : a publication of the Ecological Society of America·2024
Same journal

A Pilot Study on Disposal Practices and Environmental Awareness of Insulin-Related Devices Among People With Diabetes.

Journal of diabetes science and technology·2026
Same journal

Quality of In-Use Insulin Under Real-World Storage Conditions in Mwanza, Tanzania.

Journal of diabetes science and technology·2026
Same journal

Continuous Glucose Monitoring Metrics for Predicting Adverse Neonatal Outcomes in Individuals Undergoing Gestational Diabetes Screening.

Journal of diabetes science and technology·2026
Same journal

Diabetes Technologist: Optimal Use of Technology in Everyday Practice.

Journal of diabetes science and technology·2026
Same journal

AI-Driven Diabetes Care and Its Relevance in the Philippine Context: Opportunities and Persistent Digital Barriers.

Journal of diabetes science and technology·2026
Same journal

Ease of Use, Ease of Learning, and Convenience of the CagriSema Dual-Chamber Pen: Results From a Usability Study in Adults With Overweight, Obesity, or Type 2 Diabetes.

Journal of diabetes science and technology·2026
See all related articles

Related Experiment Video

Updated: Apr 28, 2026

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing
06:55

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing

Published on: May 8, 2021

5.1K

Validity and Reliability of a Glucometer Against Industry Reference Standards.

Amanda J Salacinski1, Micah Alford2, Kathryn Drevets2

  • 1Department of Kinesiology and Physical Education, Northern Illinois University, DeKalb, IL, USA asalacinski@niu.edu.

Journal of Diabetes Science and Technology
|May 31, 2014
PubMed
Summary
This summary is machine-generated.

Portable glucometers showed poor accuracy and reliability in a biomedical research setting. These devices are suitable for patient management but not for research or clinical diagnosis.

Keywords:
accuracybiasoral glucose tolerance testreproducibility

More Related Videos

Bergmeyer Glucose Quantification for Microbiological Samples
07:23

Bergmeyer Glucose Quantification for Microbiological Samples

Published on: January 17, 2025

1.6K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.7K

Related Experiment Videos

Last Updated: Apr 28, 2026

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing
06:55

Low-Cost, Volume-Controlled Dipstick Urinalysis for Home-Testing

Published on: May 8, 2021

5.1K
Bergmeyer Glucose Quantification for Microbiological Samples
07:23

Bergmeyer Glucose Quantification for Microbiological Samples

Published on: January 17, 2025

1.6K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.7K

Area of Science:

  • Biomedical Engineering
  • Clinical Chemistry
  • Human Physiology

Background:

  • Portable glucometers are widely used for self-monitoring blood glucose levels.
  • Their accuracy and precision are critical for reliable health management and research.
  • Evaluating glucometer performance against reference standards is essential.

Purpose of the Study:

  • To assess the accuracy, precision, and bias of a portable glucometer in a biomedical research context.
  • To compare glucometer readings against a reference laboratory analyzer during an oral glucose tolerance test (OGTT).

Main Methods:

  • A cohort of 15 healthy, active young adults underwent an OGTT with varying glucose loads (50, 75, 150g).
  • Blood glucose levels were measured concurrently using a portable glucometer and a reference laboratory instrument.
  • Statistical analysis evaluated the agreement, precision, and bias between the two measurement methods.

Main Results:

  • Only 39% of glucometer readings fell within 15% of the reference instrument's measurements across a glucose range of 45.05 to 169.37 mg/dL.
  • The glucometer exhibited both proportional and fixed biases compared to the reference analyzer.
  • The study indicated poor validity and reliability of the glucometer for research applications.

Conclusions:

  • The tested portable glucometer demonstrated inadequate performance for biomedical research, diagnosis, or treatment decisions.
  • While useful for general patient management, its limitations preclude its use in research settings requiring high accuracy.
  • Further validation studies are needed to determine the suitability of portable glucometers for specific clinical and research applications.