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Updated: Apr 28, 2026

Adipo-Clear: A Tissue Clearing Method for Three-Dimensional Imaging of Adipose Tissue
Published on: July 28, 2018
Optical architecture design for detection of absorbers embedded in visceral fat
Robert Francis1, James Florence1, Duncan MacFarlane2
1Raytheon EO Innovations, 1601 N Plano Rd, Richardson, TX 75081, USA ; Department of Electrical Engineering, University of Texas Dallas, 800 W Campbell Rd, Richardson, TX 75080, USA.
Abstract:
Optically absorbing ducts embedded in scattering adipose tissue can be injured during laparoscopic surgery. Non-sequential simulations and theoretical analysis compare optical system configurations for detecting these absorbers. For absorbers in deep scattering volumes, trans-illumination is preferred instead of diffuse reflectance. For improved contrast, a scanning source with a large area detector is preferred instead of a large area source with a pixelated detector.

