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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Related Experiment Video

Updated: Apr 28, 2026

Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
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Evolving ablative therapies for hepatic malignancy.

Smit Singla1, Steven N Hochwald1, Boris Kuvshinoff1

  • 1Roswell Park Cancer Institute, Elm and Carlton Street, Buffalo, NY 14263, USA.

Biomed Research International
|May 31, 2014
PubMed
Summary
This summary is machine-generated.

Liver cancer treatments are limited, but tumor ablation offers a promising alternative for many patients. Further research is needed to confirm long-term benefits and establish optimal comparative methodologies for evaluating ablation techniques.

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Area of Science:

  • Hepatology
  • Surgical Oncology
  • Interventional Radiology

Background:

  • The liver is a frequent site for primary and secondary cancers.
  • Curative treatments like resection and transplantation are only suitable for 10-20% of patients.
  • Tumor ablation is a key alternative for unresectable liver malignancies.

Purpose of the Study:

  • To highlight tumor ablation as a promising treatment for liver cancer.
  • To discuss the role of ablation in local control, survival, and downstaging.
  • To emphasize the need for rigorous evaluation of newer ablative techniques.

Main Methods:

  • Review of current literature on liver tumor ablation techniques.
  • Discussion of palliative versus potentially curative applications of ablation.
  • Emphasis on comparative outcome methodologies for evaluating ablation efficacy.

Main Results:

  • Tumor ablation provides local control and improves survival in liver cancer patients.
  • Ablation can downstage patients for curative therapies, used alone or in combination.
  • Newer ablative techniques are shifting focus from palliation to curative potential.

Conclusions:

  • Tumor ablation is a vital treatment option for patients with unresectable liver tumors.
  • Ongoing evaluation using comparative methodologies is crucial for understanding long-term safety and survival benefits.
  • Advancements in ablation techniques offer hope for improved outcomes in liver cancer management.