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Updated: Apr 28, 2026

Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
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Why is everyone so excited about thromboelastrography (TEG)?

Brad S Karon1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|June 1, 2014
PubMed
Summary

Thromboelastography (TEG), a whole-blood viscoelastic test, offers insights into coagulation defects missed by routine tests. TEG can improve outcomes and reduce transfusions in critically ill patients but requires careful attention to unique testing variables.

Keywords:
Critical careThromboelastographyViscoelastic coagulation testing

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Area of Science:

  • Clinical Laboratory Medicine
  • Hemostasis and Thrombosis
  • Critical Care Medicine

Background:

  • Thromboelastography (TEG) is a widely used whole-blood viscoelastic coagulation test.
  • TEG detects coagulation abnormalities often missed by routine tests like PT and aPTT.
  • Its application in critically ill patients may improve outcomes and reduce transfusions.

Purpose of the Study:

  • To review the principles, clinical applications, and laboratory aspects of TEG testing.
  • To highlight TEG's advantages over routine coagulation tests.
  • To discuss the unique pre-analytic and analytic variables affecting TEG.

Main Methods:

  • Literature review of TEG principles, applications, and laboratory considerations.
  • Comparison of TEG with routine laboratory coagulation tests.
  • Discussion of pre-analytic and analytic factors influencing TEG results.

Main Results:

  • TEG provides comprehensive hemostasis information.
  • TEG can guide transfusion strategies in specific patient groups.
  • TEG is sensitive to unique pre-analytic and analytic variables.

Conclusions:

  • TEG is a valuable tool for assessing coagulation in clinical settings.
  • Understanding TEG's specific variables is crucial for accurate interpretation.
  • Further research into TEG optimization and application is warranted.