Related Experiment Video
Updated: Apr 28, 2026

07:26
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
1.7K
[Tooth eruption disturbances and syndromes].
Nederlands Tijdschrift Voor Tandheelkunde
|June 3, 2014
Summary
Gene mutations can disrupt tooth eruption, leading to syndromes where teeth fail to erupt. Dentists play a key role in identifying these eruption problems, often requiring geneticist consultation.
Area of Science:
- Genetics
- Developmental Biology
- Dentistry
Context:
- Tooth eruption is a complex biological process.
- Disruptions can stem from genetic mutations.
- Several rare syndromes are characterized by complete tooth eruption failure.
Purpose:
- To highlight the vulnerability of the tooth eruption mechanism.
- To identify key syndromes associated with tooth eruption failure.
- To emphasize the role of dentists in diagnosing these issues.
Summary:
- Gene mutations can cause significant disturbances in tooth eruption.
- Five specific syndromes (cleidocranial dysplasia, Gardner's syndrome, osteopetrosis, mucopolysaccharidosis, GAPO syndrome) result in the complete failure of tooth eruption.
- While rare, these syndromes underscore the delicate nature of tooth development.
Impact:
- Dentists are often the first to identify tooth eruption problems.
- Suspicion of a syndrome necessitates further investigation by a clinical geneticist due to potential associated disorders.
Related Concept Videos
Teeth
2.2K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
2.2K
Tooth Anatomy
2.7K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.7K
Development of the Oral Microbiota
65
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
65
Psychosexual Stages of Personality: Oral
3.9K
The oral stage is the initial phase of Sigmund Freud's theory of psychosexual development, occurring from birth to approximately 12 to 18 months. During this period, the infant's mouth serves as the primary source of pleasure, with actions such as sucking, chewing, biting, and drinking playing a crucial role in reducing tension. These activities are essential not only for nourishment but also for the infant's psychological and emotional satisfaction.
Weaning, typically occurring...
Weaning, typically occurring...
3.9K
Oral Cavity
3.7K
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
3.7K
Assessment of the Mouth
1.6K
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.6K

