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Pineal malignant B-cell lymphoma with lower cranial nerve involvement
Takeshi Yoshida1, Yukio Tezuka, Takanobu Hirosawa
1Department of Neurology, Okinawa Chubu Hospital, Japan.
Internal Medicine (Tokyo, Japan)
|June 3, 2014
Summary
Diffuse large B-cell lymphoma can present as a pineal region tumor, causing symptoms like dysphagia and hoarseness. Histological confirmation is vital for accurate diagnosis and treatment of this rare presentation.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- A 62-year-old male presented with acute onset dysphagia and hoarseness.
- Neurological examination revealed bulbar palsy, suggesting cranial nerve involvement.
Observation:
- Brain MRI demonstrated thickened cranial nerves IX, X, and XI.
- Enlargement of the pineal body with diffuse contrast enhancement was noted.
Findings:
- Histological analysis of a biopsy from the spinal root of the right XIth cranial nerve confirmed diffuse large B-cell lymphoma.
- This indicates a rare presentation of malignant lymphoma in the pineal region.
Implications:
- Malignant lymphoma should be included in the differential diagnosis for pineal region tumors.
- Histological confirmation is essential for appropriate patient management and treatment planning.
