Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diagnostic and Statistical Manual of Mental Disorders (DSM)

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...

Schizophrenia

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...

Psychological and Sociocultural Causes of Schizophrenia

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

Positive Symptoms Schizophrenia: Hallucinations and Delusions

Positive Symptoms Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...

Biological Causes of Schizophrenia

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Some notes on the near future].

Vertex (Buenos Aires, Argentina)·2015

Same author

[DSM-5: lights and shadows].

Vertex (Buenos Aires, Argentina)·2014

Same author

[Side effects of psychopharmaceuticals and the problem of the "short blanket"].

Vertex (Buenos Aires, Argentina)·2009

Same author

[Metabolic syndrome induced by antipsychotic drugs. The problem of obesity].

Vertex (Buenos Aires, Argentina)·2009

Same author

[Adverse effects of psychiatric drugs on glucose and lipids metabolism].

Vertex (Buenos Aires, Argentina)·2005

Search research articles

Related Experiment Video

Updated: Apr 28, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

[Schizophrenia according to DSM-5].

Gabriela S Jufe¹

¹Hospital de Emergencias Psiquiátricas T. de Alvear, CABA. gsjufe@gmail.com.

Vertex (Buenos Aires, Argentina)

|June 3, 2014

Summary

The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) updated schizophrenia criteria, removing subtype classifications and clarifying symptom definitions for improved psychiatric disorder diagnosis.

Area of Science:

Psychiatry
Psychopathology
Clinical Psychology

Context:

The classification of psychiatric disorders has undergone significant evolution over the past 50 years.
The Diagnostic and Statistical Manual of Mental Disorders (DSM) is a key resource for psychiatric diagnosis.
The DSM-5 introduced substantial revisions to the schizophrenia spectrum and other psychotic disorders chapter.

Purpose:

To review modifications in the DSM-5 chapter on schizophrenia spectrum and other psychotic disorders.
To analyze specific changes implemented for the diagnosis of schizophrenia in DSM-5.
To discuss the implications of these diagnostic revisions and the absence of validated biomarkers.

Summary:

DSM-5 eliminated the special emphasis on Schneiderian "first-rank" symptoms for schizophrenia.

More Related Videos

Development of a Virtual Reality Assessment of Everyday Living Skills

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Related Experiment Videos

Last Updated: Apr 28, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

Development of a Virtual Reality Assessment of Everyday Living Skills

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Negative symptoms in schizophrenia are now more clearly defined.

Schizophrenia diagnosis in DSM-5 requires at least one symptom to be disorganized speech, hallucinations, or delusions.

Subtypes of schizophrenia were removed, and psychopathological dimensions were introduced.

The lack of validated biomarkers for diagnosis is discussed as a continuing challenge.

Impact:

These changes aim to refine schizophrenia diagnosis and classification within the DSM system.
The revisions reflect an evolving understanding of psychotic disorders.
The discussion highlights the ongoing need for objective diagnostic tools in psychiatry.