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Oxygen detoxifying enzymes in parasites: a review
R W Leid1, C M Suquet, L Tanigoshi
1Department of Veterinary Microbiology/Pathology, Washington State University, Pullman 99164-7040.
Acta Leidensia
|January 1, 1989
Abstract:
This review focuses on parasite enzymes which are involved in the detoxification of oxygen radicals, and covers the following enzymes: superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and glutathione reductase. These enzymes are crucial for parasites to evade oxygen-mediated attack by host leukocytes, both intracellularly and extracellularly. In addition, the newly defined parasite system involving trypanothione, trypanothione peroxidase and trypanothione reductase is discussed.