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Updated: Apr 28, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Lymphangiogenesis: implications for diagnosis, treatment, and prognosis in patients with melanoma
I Pastushenko1, C Conejero1, F J Carapeto2
1Servicio de Dermatología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
Abstract:
Disease course in melanoma often cannot be accurately predicted by means of the prognostic factors usually considered in patients with melanoma; therefore, new factors are clearly needed. Increasingly robust scientific evidence shows that tumor lymph vessels play a key role in melanoma that metastasizes by lymphatic and hematogenous pathways. We review current knowledge and examine the implications of lymphangiogenesis in the diagnosis, treatment, and prognosis of patients with melanoma.
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