Related Experiment Video
Updated: Apr 28, 2026

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography
Published on: November 24, 2016
Imaging QRS complex and ST segment in myocardial infarction.
Ljuba Bacharova1, Lia E Bang2, Vavrinec Szathmary3
1International Laser Center, 841 04 Bratislava, Slovak Republic; Institute of Pathological Physiology, Medical Faculty, Comenius University, Bratislava, Slovak Republic.
This study introduces a graphical method using Dipolar ElectroCARdioTOpography (DECARTO) to visualize electrical changes in myocardial infarction. It effectively images altered depolarization sequences and ST segment deviations, aiding in understanding heart attack impacts.
Area of Science:
- Cardiology
- Medical Imaging
- Electrophysiology
Background:
- Acute myocardial infarction (MI) alters cardiac electrical properties, leading to characteristic ECG changes like pathological Q waves and ST deviations.
- These electrical changes reflect the location and extent of myocardial damage.
Purpose of the Study:
- To present a graphical imaging method for visualizing changes in myocardial depolarization sequence and ST segment deviations in MI.
- To utilize the Dipolar ElectroCARdioTOpography (DECARTO) method for this purpose.
Main Methods:
- Simulated ECG data from models with electrically inactive and slowed conduction areas were used.
- ECG data were transformed into projected images to visualize ventricular depolarization and estimate "myocardium at risk" from ST segment deviation.
Main Results:
- The DECARTO method generated Mercator projections showing anatomical segments and coronary artery distribution.
- Altered depolarization sequences appeared as dislocations around affected areas.
- "Myocardium at risk" was accurately identified by ST segment deviation.
Conclusions:
- The developed ECG imaging method visually represents depolarization sequence changes and ST segment deviations in MI.
- This technique allows for visual comparison with other non-ECG imaging modalities.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome I: Introduction
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Electrocardiogram Fundamentals
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
Myocarditis II: Clinical Features and Diagnostic Tests

