Related Experiment Video

Updated: Apr 28, 2026

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
05:21

A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection

Published on: August 14, 2019

28.9K

Influenza and parainfluenza viral infections in children

Thomas G Fox1, John C Christenson1

  • 1Department of Pediatrics, Ryan White Center for Pediatric Infectious Disease, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN.

Pediatrics in Review
|June 4, 2014
PubMed

Insights

Influenza and parainfluenza viruses cause significant illness in vulnerable populations. Influenza vaccines are safe and effective for children and pregnant women, protecting infants under six months.

Area of Science:

  • Pediatric infectious diseases
  • Vaccinology
  • Respiratory viral infections

Background:

  • Influenza and parainfluenza viruses are major causes of illness and death in young children and those with chronic health issues.
  • These viruses pose a significant public health burden, necessitating effective prevention and treatment strategies.

Purpose of the Study:

  • To evaluate the efficacy and safety of influenza vaccines in pediatric populations.
  • To assess the role of influenza and parainfluenza viruses in pediatric morbidity and mortality.
  • To review treatment options for laryngotracheitis caused by parainfluenza viruses.

Main Methods:

  • Review of epidemiologic evidence on influenza and parainfluenza virus infections.
  • Analysis of research evidence on influenza vaccine effectiveness and safety in children.
  • Examination of studies on the use of corticosteroids and epinephrine for laryngotracheitis.

Main Results:

  • Influenza vaccines are proven effective and safe for children aged 6 months and older.
  • Vaccination of pregnant mothers is a key strategy to protect infants under 6 months from influenza.
  • Corticosteroids and epinephrine show benefit in treating parainfluenza-induced laryngotracheitis.

Conclusions:

  • Influenza vaccination is a critical preventive measure for high-risk children and infants.
  • Parainfluenza virus infections require specific treatment considerations for laryngotracheitis.
  • Public health strategies should prioritize influenza vaccination in pregnant women and young children.

More Related Videos

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice10:47

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Published on: April 14, 2011

17.1K
Influenza A Virus Studies in a Mouse Model of Infection10:44

Influenza A Virus Studies in a Mouse Model of Infection

Published on: September 7, 2017

28.8K

Related Concept Videos

Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
79
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
191
Vaccinations01:51

Vaccinations

Overview
44.0K
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
23
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.4K
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
22.2K