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Uveodermatologic syndrome concurrent with keratoconjunctivitis sicca in a miniature poodle dog
Min-Hee Kang1, Chae-Young Lim1, Hee-Myung Park1
1Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, 143-701 South Korea.
Summary
Uveodermatologic syndrome (UDS) in a miniature poodle presented with eye and skin issues. While immunosuppressants treated skin lesions, the progressive uveitis remained a challenge.
Area of Science:
- Veterinary Ophthalmology
- Veterinary Dermatology
- Immunology
Background:
- Uveodermatologic syndrome (UDS) is an autoimmune condition affecting the eyes and skin.
- Keratoconjunctivitis sicca (KCS) is a common ocular surface disease in dogs.
Observation:
- A 5-year-old miniature poodle exhibited chronic ophthalmic issues, facial poliosis, nasal depigmentation, and alopecia.
- Bilateral uveitis preceded dermatologic manifestations by 5 months and showed progressive worsening.
Findings:
- The dog was diagnosed with concurrent uveodermatologic syndrome (UDS) and keratoconjunctivitis sicca (KCS).
- Immunosuppressive therapy successfully resolved dermatologic lesions.
- Ocular inflammation (uveitis) persisted despite treatment.
Implications:
- This case highlights the complexity of managing concurrent UDS and KCS in dogs.
- Refractory uveitis in UDS cases may require alternative or adjunctive therapeutic strategies.
- Further research into the immunopathogenesis of UDS is warranted to improve treatment outcomes.
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