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Alcoholic pancreatitis: A tale of spirits and bacteria

Alain Vonlaufen1, Laurent Spahr1, Minoti V Apte1

  • 1Alain Vonlaufen, Gastroenterology Unit, Hôpital de la Tour, 1217 Meyrin/Genève, Switzerland.

World Journal of Gastrointestinal Pathophysiology
|June 4, 2014
PubMed

Keywords:
AlcoholBacteriaEndotoxinFibrosisLipopolysaccharidePancreatitis

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Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...
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