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Related Experiment Video

Updated: Apr 28, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
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Orbital Involvement by NUT Midline Carcinoma.

Jill N D'Souza1, Gregory Notz, Ronald N Bogdasarian

  • 1*Department of Otolaryngology/Head Neck Surgery, Thomas Jefferson University Hospital, Philadelphia; †Department of Ophthalmology, Geisinger Health System, Danville; ‡The Commonwealth Medical College, Scranton; §Department of Pathology; ‖Department of Neurosurgery, Thomas Jefferson University Hospital; and ¶Skull Base Division, Neuro-Ophthalmology Service, Wills Eye Hospital, Philadelphia, Pennsylvania, U.S.A.

Ophthalmic Plastic and Reconstructive Surgery
|June 4, 2014
PubMed
Summary
This summary is machine-generated.

NUT midline carcinoma, an aggressive cancer, can affect the orbit. This report details a rare case of orbital NUT midline carcinoma, discussing its features and treatment.

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Area of Science:

  • Oncology
  • Pathology
  • Ophthalmology

Background:

  • NUT midline carcinoma is an aggressive malignancy with a poor prognosis.
  • Orbital involvement is exceptionally rare, with limited documented cases.

Observation:

  • A 32-year-old female presented with a sino-orbital mass.
  • Imaging revealed a lesion involving the orbit and paranasal sinuses.

Findings:

  • Histopathological examination confirmed the diagnosis of NUT midline carcinoma.
  • This represents the third reported case of orbital NUT midline carcinoma.

Implications:

  • Understanding the clinical, radiographic, and histopathologic features is crucial for diagnosis.
  • Management strategies for this rare presentation require careful consideration.