Related Experiment Video
Updated: Apr 28, 2026

07:25
Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury
Published on: May 25, 2017
11.3K
Basic aspects in MR imaging of degenerative lumbar disk disease
Andreas Heuck1, Christian Glaser1
1Radiologisches Zentrum München (RZM), Munich Germany.
Seminars in Musculoskeletal Radiology
|June 5, 2014
Summary
Degenerative disc disease can cause spinal stenosis and chronic pain, impacting work ability. This review covers disk anatomy, degeneration, herniation imaging, and standardized terminology for better clinical communication.
Area of Science:
- Radiology and Imaging
- Orthopedics
- Neurosurgery
Background:
- Degenerative diseases frequently lead to spinal canal stenosis and persistent pain, significantly contributing to disability.
- The aging population is experiencing a rise in these conditions, increasing the need for effective diagnostic tools.
- Magnetic Resonance Imaging (MRI) offers comprehensive morphologic detail crucial for understanding spinal pathologies.
Purpose of the Study:
- To review the normal anatomy of the intervertebral disk.
- To elucidate the pathologic mechanisms underlying disk degeneration and herniation.
- To present a standardized terminology for imaging findings and discuss the spectrum of disk pathology.
Main Methods:
- Review of literature on intervertebral disk anatomy and pathology.
- Analysis of imaging findings from Magnetic Resonance Imaging (MRI).
- Synthesis of standardized terminology for disk degeneration and herniation.
Main Results:
- Detailed description of normal intervertebral disk anatomy.
- Explanation of key pathologic mechanisms in disk degeneration.
- Illustrative examples of imaging findings for disk degeneration and herniation.
Conclusions:
- Standardized terminology in spinal imaging improves communication between radiologists and referring physicians.
- Accurate interpretation of imaging findings, combined with clinical data, is essential for guiding therapeutic decisions.
- Understanding the imaging spectrum of disk degeneration and herniation aids in diagnosing and managing spinal conditions.
Related Concept Videos
Degenerative Disc Disease I: Introduction
26
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
26
Degenerative Disc Disease ll: Pathophysiology
28
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
28
Herniated Intervertebral Disc l: Introduction
38
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
38
Magnetic Resonance Imaging
7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K

