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Updated: Apr 28, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography
Published on: January 11, 2020
An unusual case of anaphylaxis after fluorine-18-labeled fluorodeoxyglucose injection
Dong Yun Lee1, Jong Jin Lee1, Hyouk-Soo Kwon2
1Department of Nuclear Medicine, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736 South Korea.
Abstract:
[(18)F]FDG (fluorine-18 fluoro-2-deoxy-D-glucose) positron emission tomography (PET) is used worldwide for oncologic and neurologic applications. To date, the potential harm caused by [(18)F]FDG has focused on its radiation exposure effects rather than on its pharmacological effects. While an allergic response in the form of a skin manifestation has been reported after exposure to [(18)F]FDG, this report describes the first case of hypotension following exposure to this tracer. Here, the development of anaphylaxis after [(18)F]FDG injection is described.
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