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Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
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Nanomaterials for (Nano)medicine.
Silvia Marchesan1, Maurizio Prato1
1Center of Excellence for Nanostructured Materials, INSTM, Unit of Trieste, Dipartimento di Scienze Chimiche e Farmaceutiche, Università degli Studi di Trieste , Piazzale Europa 1, 34127 Trieste, Italy.
ACS Medicinal Chemistry Letters
|June 6, 2014
Summary
Medicinal chemists can leverage advanced nanomaterials for next-generation nanomedicine. This review highlights promising candidates offering unprecedented performance for drug delivery and therapeutic applications.
Area of Science:
- * Nanomedicine and Materials Science
- * Medicinal Chemistry
- * Nanotechnology
Background:
- * Next-generation nanomedicine demands novel nanomaterials with superior capabilities.
- * Current limitations in existing nanomaterials necessitate exploration of new candidates.
- * Medicinal chemists require an understanding of emerging materials for therapeutic innovation.
Purpose of the Study:
- * To identify and review promising nanomaterials for advanced nanomedicine applications.
- * To guide medicinal chemists in selecting optimal materials for drug delivery and therapy.
- * To provide insights into the performance characteristics of innovative nanomaterials.
Main Methods:
- * Comprehensive literature review of recent advancements in nanomaterial science.
- * Analysis of material properties relevant to medicinal chemistry and drug delivery.
- * Evaluation of performance metrics for potential nanomedicine applications.
Main Results:
- * Identification of several classes of nanomaterials with high potential, including lipid nanoparticles, polymer-based nanoparticles, and inorganic nanoparticles.
- * Detailed discussion of their unique properties, such as biocompatibility, drug loading capacity, and targeted delivery capabilities.
- * Assessment of their current stage of development and potential challenges for clinical translation.
Conclusions:
- * Innovative nanomaterials are crucial for advancing nanomedicine.
- * Lipid, polymer, and inorganic nanoparticles represent key candidates for medicinal chemists.
- * Further research and development are needed to fully realize the therapeutic potential of these advanced materials.
