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[Sepsis and neonatal meningitis].

J Bosch, F Borja, E Alvarez

    Enfermedades Infecciosas Y Microbiologia Clinica
    |January 1, 1989
    PubMed
    Summary

    Neonatal meningitis and sepsis affect 3.33 per 1000 live neonates, with neurological symptoms common. Early diagnosis and treatment are crucial for reducing the 7.9% mortality rate in these vulnerable infants.

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    Unsupervised Quark/Gluon Jet Tagging With Poissonian Mixture Models.

    Frontiers in artificial intelligence·2022

    Area of Science:

    • Neonatal infectious diseases
    • Pediatric infectious disease epidemiology
    • Bacteriology in neonates

    Context:

    • Neonatal meningitis and sepsis are serious infections in infants under 28 days.
    • Prematurity, low birth weight, and unfavorable obstetrical history are significant risk factors.
    • Understanding the clinical and microbiological profiles is essential for effective management.

    Purpose:

    • To retrospectively review epidemiological, clinical, and bacteriological data of neonatal infections.
    • To identify common causative microorganisms and clinical presentations.
    • To determine the incidence and mortality rates of neonatal meningitis and sepsis.

    Summary:

    • This study analyzed 38 neonates diagnosed with meningitis, early, or late sepsis.
    • Predominant clinical features included neurological, cardiac, and respiratory symptoms.
    • Key pathogens identified were E. coli, S. agalactiae, and S. aureus, with an overall mortality of 7.9%.

    Impact:

    • Highlights the significant burden of neonatal infections, with E. coli and S. agalactiae as major pathogens.
    • Emphasizes the need for prompt recognition of neurological and systemic signs in neonates.
    • Provides crucial data on incidence and mortality, informing public health strategies and clinical practice for neonatal sepsis and meningitis.

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