Cyclodextrin-coated denim fabrics as novel carriers for ingredient deliveries to the skin
Hamideh Issazadeh-Baltorki1, Akbar Khoddami1
1Department of Textile Engineering, Isfahan University of Technology, Isfahan 84156-83111, Islamic Republic of Iran.
Abstract:
Garments with coverage of a large part of the body generate an exceptional opportunity for transferring active ingredient to the skin. A fabric finished with β-cyclodextrin derivatives can play a role as a host for a next active substance as a guest. In this paper, different methods for permanent fixation of Monochlorotriazinyl-β-Cyclodextrin (MCT)-β-CD, on inner side of a denim fabric were investigated as a carrier with the purpose of substance formation inclusion complex with (MCT)-CD hydrophobic cavity. In order to fix MCT-CD on the fabric surface, two methods were investigated: (1) simultaneously or one step- and (2) pre- or two step-carbonating with sodium carbonate. Varying chemical and physical analyses such as gravimetrical and elemental analysis, FTIR spectroscopy, SEM images and fastness properties measurements, were studied to evaluate the quality of the host molecule stabilization on the textiles substrates and distinction of better application method.
More Related Videos
Related Concept Videos
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Transdermal Drug Delivery Systems
Drug Delivery: Overview
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Drug Delivery Systems: Different Types
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention


