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Updated: Apr 28, 2026

Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
Published on: May 16, 2019
[Therapeutic strategy for mental symptoms in people with epilepsy]
Abstract:
Epilepsy has an association with nearly all types of psychiatric problems and psychiatric symptoms are common clinical manifestations seen in epilepsy patients. For example, interictal depression in individuals with epilepsy is more prevalent than in the general population or among patients with other chronic disorders. The high frequency of depression and clinical impact of psychosis in epilepsy have been well documented in recent studies, indicating the importance of diagnosing and treating psychiatric implications in affected patients. This article reviews various psychiatric symptoms such as postictal psychosis, interictal psychosis, depression, psychogenic non-epileptic seizure(PNES), and cognitive dysfunction encountered in patients with epilepsy.
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