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Blood component therapy in open heart surgery.
1Blood Donor Center, Sudbury, Canada.
Materia Medica Polona. Polish Journal of Medicine and Pharmacy
|July 1, 1989
Summary
Platelet transfusions can correct bleeding from low platelet counts in surgery. However, fresh frozen plasma is rarely needed for cardiopulmonary bypass bleeding, which is often due to platelet dysfunction.
Area of Science:
- Surgical Hemostasis
- Transfusion Medicine
Background:
- Extensive surgical bleeding remains a significant cause of patient morbidity and mortality.
- Modern blood component therapy and hemostasis understanding have improved outcomes, but challenges persist.
Purpose of the Study:
- To evaluate the role of platelet transfusions in managing surgical bleeding.
- To assess the necessity of fresh frozen plasma (FFP) in cardiopulmonary bypass operations.
Main Methods:
- Review of clinical and laboratory data for platelet transfusion requests.
- Analysis of hemostatic alterations during cardiopulmonary bypass.
- Comparison of historical and current blood usage in open heart surgery.
Main Results:
- Platelet concentrates can correct bleeding due to thrombocytopenia or thrombocytopathia.
- Bleeding during cardiopulmonary bypass is often linked to platelet dysfunction, not plasma coagulation issues.
- Fresh frozen plasma is rarely required; mild coagulation abnormalities are often tolerated.
Conclusions:
- Platelet transfusion decisions should integrate clinical, laboratory data, and underlying conditions.
- Stored red blood cells are effective in open heart surgery.
- Hemodilution techniques effectively reduce blood usage in cardiopulmonary bypass.