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Feedback Loops01:01

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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
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Updated: Apr 28, 2026

Analysis of Circadian Photoresponses in Drosophila Using Locomotor Activity
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Author's Reply

Rajesh K Chudasama1, Pramod B Verma1, Chikitsa D Amin1

  • 1Department of Community Medicine, Government Medical College, Rajkot, Gujarat, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|June 11, 2014
PubMed
Summary

No abstract available in PubMed .

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