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Odontogenic keratocyst in a cat
E E B LaDouceur1, K S Walker2, F C Mohr1
1Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.
Journal of Comparative Pathology
|June 12, 2014
Summary
This study reports the first case of an odontogenic keratocyst in a cat. This rare, locally invasive cyst presented as a mandibular swelling, requiring diagnosis through radiography and histology.
Area of Science:
- Veterinary Pathology
- Oral Surgery
Background:
- Odontogenic cysts, rare in felines, originate from odontogenic epithelium and can cause local invasion.
- This study focuses on a specific type, the odontogenic keratocyst, typically seen in humans.
Observation:
- A 16-year-old domestic shorthair cat presented with a 3-year history of progressive right mandibular swelling.
- Radiographs revealed a multilocular, radiolucent cystic mass causing bone destruction and tooth root resorption.
Findings:
- Histological examination confirmed cysts lined by stratified squamous epithelium of odontogenic origin, containing significant keratin.
- The features were consistent with odontogenic keratocyst, a diagnosis previously unreported in cats.
Implications:
- This case establishes the occurrence of odontogenic keratocysts in cats, expanding the differential diagnosis for feline mandibular masses.
- Highlights the importance of advanced imaging and histopathology for accurate diagnosis and treatment planning in veterinary dentistry.

