Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cerebellum: Anatomical Regions

Cerebellum: Anatomical Regions

The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...

Major Somatic Sensory Pathways

Major Somatic Sensory Pathways

Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...

Role of Cerebellum and Prefrontal Cortex in Memory

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...

Diencephalon: Thalamus and Information Relay

Diencephalon: Thalamus and Information Relay

The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...

Brainstem

Brainstem

The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...

Cerebrum: Anatomical Overview II

Cerebrum: Anatomical Overview II

Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Impact of Sema3A Interference on Cerebellum-Dependent Motor Associative Learning and Memory.

International journal of molecular sciences·2026

Same author

Emotional and attentional anomalies underlying triarchic psychopathic traits: an EEG-startle blink study.

BMC psychology·2026

Same author

Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology.

Autism research : official journal of the International Society for Autism Research·2026

Same author

Neurobiological mechanisms underlying the beneficial effects of music interventions in perioperative care: a narrative review.

Acta psychologica·2025

Same author

Aberrant neural activity in the peritumoral cortex underlies the progression of tumor-associated seizures.

Nature communications·2025

Same author

Duration of music listening in music-induced analgesia: A pilot randomized controlled trial.

Complementary therapies in medicine·2025

Search research articles

Related Experiment Video

Updated: Apr 28, 2026

Cerebellar Regional Dissection for Molecular Analysis

Cerebellar Regional Dissection for Molecular Analysis

Published on: December 5, 2020

Questioning the cerebellar doctrine.

Elisa Galliano¹, Chris I De Zeeuw²

¹Department of Neuroscience, Erasmus MC Rotterdam, Rotterdam, The Netherlands.

Progress in Brain Research

|June 12, 2014

Summary

This summary is machine-generated.

The classic cerebellar doctrine, focused on motor control and learning via Purkinje cells, is being re-examined. This review synthesizes new findings to propose a revisited version of cerebellar function.

Keywords:

climbing fibers cognitive and emotional behavior distributed synergistic plasticity input convergence mossy fibers motor behavior motor learning timing control

More Related Videos

Understanding Cerebellar Pattern Formation

Understanding Cerebellar Pattern Formation

Published on: November 1, 2007

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

Related Experiment Videos

Last Updated: Apr 28, 2026

Cerebellar Regional Dissection for Molecular Analysis

Cerebellar Regional Dissection for Molecular Analysis

Published on: December 5, 2020

Understanding Cerebellar Pattern Formation

Understanding Cerebellar Pattern Formation

Published on: November 1, 2007

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

Area of Science:

Neuroscience
Cerebellar Function

Background:

The classic cerebellar doctrine posits motor control and learning as primary functions.
Key elements include Purkinje cells integrating climbing and mossy-parallel fiber inputs.
Synaptic plasticity at parallel fiber synapses is considered the basis of motor learning.

Purpose of the Study:

To review the foundational principles of cerebellar function.
To examine recent challenges and disputes to the classic cerebellar doctrine.
To propose an integrated and revisited version of the cerebellar doctrine.

Main Methods:

Literature review of classic cerebellar concepts.
Analysis of recent technical advances and new research angles.
Synthesis of existing knowledge and new findings.

Main Results:

The pillars of the classic cerebellar doctrine are under re-examination.
New technical advances offer novel perspectives on cerebellar function.
Integration of classic and recent findings is necessary.

Conclusions:

A revisited cerebellar doctrine is proposed.
The cerebellum's role may extend beyond motor control.
Future research should integrate diverse findings for a comprehensive understanding.