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Auditory brainstem response: reference-values for age
Luana Araujo Cruz Rosa1, Marcia Rumi Suzuki1, Rosanna Giaffredo Angrisani2
1Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Insights
Auditory brainstem response latencies in newborns and infants decrease with age. This study establishes reference values for wave I, III, and V latencies in preterm newborns, term newborns, and six-month-old infants.
Area of Science:
- Neuroscience
- Pediatrics
- Audiology
Background:
- Auditory brainstem responses (ABRs) are crucial for assessing auditory pathway function in infants.
- Establishing normative ABR values is essential for early detection of hearing impairments.
Purpose of the Study:
- To determine absolute and interpeak latencies of Auditory Brainstem Responses (ABRs) in preterm newborns, term newborns, and infants at six months of age.
- To establish age-specific reference values for ABR waves I, III, and V, and interpeak latencies (I-III, III-V, I-V).
Main Methods:
- Retrospective analysis of ABR tests from 80 infants.
- Infants were categorized into four groups based on post-conceptual age: 35-36 weeks, 37-38 weeks, 39-40 weeks, and six months old.
Main Results:
- Absolute latencies for waves I, III, and V consistently decreased with increasing age across all groups.
- Interpeak latencies (I-III, III-V, I-V) also showed a significant decrease with age.
- Specific latency values were provided for each age group, indicating a maturational trend.
Conclusions:
- Auditory pathway maturation is reflected in the decreasing ABR latencies with age.
- The established reference values align with international literature, supporting their clinical utility.
Purpose:
To study the absolute latencies of waves I , III and V and interpeak I-III , III-V and I-V of Auditory brainstem responses obtained in preterm newborns in relation to post-conceptual age, term newborns and six months of age infants, establishing reference values for each age group.
Methods:
Retrospective study realized through the analysis of tests performed on 80 infants divided into four groups, being the group one composed per newborns assessed between 35 and 36 weeks post-conceptual age; group two by newborns assessed between 37 and 38 weeks; group three with newborns reviewed between 39 to 40 weeks; and group four with infants evaluated with six months.
Results:
The wave I absolute latency in the group one was 1.81 ms, decreasing to 1.79 ms in groups two and three, and to 1.70 ms in group four. The wave III latency in group one was 4.74 ms, decreasing to 4.62 ms in group two, to 4.56 ms in the group three and to 4.37 ms in the group four. The wave V latency in group one was 7.14 ms, in the group two it was 7.05 ms, in the group three 6.90 ms; and in the group four it was 6.50 ms. Interpeak latencies were also decreased in all groups.
Conclusion:
The latencies studied decreased with the increasing age and were similar values with the international literature.

