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Updated: Apr 28, 2026
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Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
Published on: July 31, 2021
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Summary
Vaccinations before and during pregnancy protect against serious infections. Key vaccines include flu and Tdap, while others are contraindicated to ensure maternal and fetal health.
Area of Science:
- Obstetrics and Gynecology
- Immunology
- Infectious Diseases
Context:
- Pregnancy necessitates careful consideration of vaccination to protect both mother and fetus.
- Maternal immunity plays a crucial role in preventing congenital infections and protecting newborns.
Purpose:
- To review infectious diseases and vaccine recommendations for women before, during, and after pregnancy.
- To provide guidance on appropriate immunizations for optimal maternal and fetal health outcomes.
Summary:
- Pre-pregnancy screening for immunity to rubella, chickenpox, and hepatitis B is recommended, with vaccination if needed.
- Vaccinations recommended before pregnancy include flu, HPV, MMR, Tdap, and chickenpox. During pregnancy, flu and Tdap (27-36 weeks) are advised.
- Contraindicated vaccines during pregnancy include BCG, MMR, meningococcal, typhoid, and varicella. Post-exposure vaccines may be considered for rabies, anthrax, smallpox, polio, and yellow fever.
- The review addresses safety concerns, noting HPV vaccination does not cause sterility.
Impact:
- Informed vaccination decisions enhance protection against preventable infectious diseases for pregnant individuals and newborns.
- Maintaining maternal immunity provides passive immunity to the fetus and infant through breastfeeding.
- Accurate information on vaccine safety and efficacy during pregnancy can alleviate patient concerns and improve adherence.
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