Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

Automated Microbial Diagnostics

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reducing Bacterial Contamination of Blood Bags with a Double Knot.

The New England journal of medicine·2026

Same author

Comparative phylogenetic, antimicrobial resistance, and clinical characterization of human spondylodiscitis-associated <i>Staphylococcus pseudintermedius</i>.

Frontiers in microbiology·2026

Same author

A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial.

Journal of psychiatric research·2026

Same author

Cannabis Use and Glutamate across the Psychosis Spectrum: In Vivo Evidence from 7T Proton Magnetic Resonance Spectroscopy.

Research square·2025

Same author

A whole-genome sequencing dataset of nanopore raw signals for bacterial genotyping and methylation analysis.

Scientific data·2025

Same author

Melioidosis in Mali: a retrospective observational study.

The Lancet. Global health·2025

Same journal

Multifunctional reconfigurable terahertz metasurface based on vanadium dioxide phase transition: achieving broadband absorption and efficient polarization conversion.

Applied optics·2026

Same journal

High-Q-factor electromagnetically induced transparency utilizing quasi-bound states in the continuum in an all-dielectric terahertz metasurface.

Applied optics·2026

Same journal

Automated stitching interferometry for high-precision metrology of X-ray mirrors.

Applied optics·2026

Same journal

Experimental demonstration of an approach to designing a metal-dielectric DBR resonant cavity structure.

Applied optics·2026

Same journal

High-precision wavefront reconstruction from a single-shot interferogram using a physics-driven hybrid feature calibration network.

Applied optics·2026

Same journal

Ultra-high-Q Fano resonance based on coupled topological corner states in Kagome photonic crystals.

Applied optics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 28, 2026

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Published on: January 30, 2016

itom: an open source metrology, automation, and data evaluation software.

Marc Gronle, Wolfram Lyda, Marc Wilke

|June 13, 2014

Summary

This summary is machine-generated.

This study introduces itom, an open-source software suite for optical sensor development. Itom provides a flexible framework for controlling hardware and processing data, enabling rapid prototyping in dynamic laboratory environments.

More Related Videos

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Published on: April 26, 2016

Precision Measurements and Parametric Models of Vertebral Endplates

Precision Measurements and Parametric Models of Vertebral Endplates

Published on: September 17, 2019

Related Experiment Videos

Last Updated: Apr 28, 2026

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Published on: January 30, 2016

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Extracting Metrics for Three-dimensional Root Systems: Volume and Surface Analysis from In-soil X-ray Computed Tomography Data

Published on: April 26, 2016

Precision Measurements and Parametric Models of Vertebral Endplates

Precision Measurements and Parametric Models of Vertebral Endplates

Published on: September 17, 2019

Area of Science:

Optical Engineering
Measurement Systems
Software Development

Background:

Modern optical sensors integrate hardware and software for complex measurements.
Developing and operating these systems requires a flexible, intuitive, and fast software framework.
Rapid prototyping in dynamic lab environments necessitates efficient hardware control and data evaluation.

Purpose of the Study:

To present the open-source measurement and data evaluation software suite, itom.
To highlight itom's design addressing the need for a flexible and performant software framework.
To showcase itom's capability in controlling hardware and processing data for optical sensor systems.

Main Methods:

Development of an open-source software suite named itom, initiated in 2011.
Integration of optical elements, active hardware components (actuators, sensing devices), and control software.
Implementation of sophisticated data evaluation and image processing algorithms within the itom framework.

Main Results:

itom provides a flexible, intuitive, and fast software framework for optical sensor development.
The software enables control and communication with diverse hardware devices.
It offers high-performance algorithms for data and image processing, facilitating rapid prototyping.

Conclusions:

itom is a comprehensive open-source solution for modern optical measurement systems.
The software suite supports the entire workflow from hardware control to data evaluation.
itom empowers researchers and developers in dynamic laboratory settings.