Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

5.7K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
5.7K
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

867
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
867
Bacterial Signaling01:30

Bacterial Signaling

29.5K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
29.5K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

4.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.7K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.1K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.1K
Infection01:20

Infection

11.4K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and microbiological features in community- and hospital-acquired extended spectrum beta lactamase producing Escherichia coli from urinary tract.

The Journal of hospital infection·2026
Same author

Peripheral neurological involvement due to Bartonella henselae in an immunocompetent adolescent: a case report and literature review.

Diagnostic microbiology and infectious disease·2026
Same author

Clinical characteristics and treatments of imported loiasis patients with microfilaraemia diagnosed in France, 2000-2022.

Travel medicine and infectious disease·2026
Same author

Spread of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) in the community living spaces of patients identified as ESBL-E carriers: impact of the housing density in an African context.

Tropical medicine and health·2026
Same author

The orphan receptor GPR84 drives inflammation in Buruli ulcer development.

Science translational medicine·2026
Same author

Re: 'Clinical utility of the DENOVA score for predicting infective endocarditis in Enterococcus faecalis bacteraemia: external validation with decision curve analysis' by Varisco et al.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026

Related Experiment Video

Updated: Apr 28, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

1.4K

[Infections associated with orthopaedic devices].

Vincent Dubée, Valérie Zeller, Bruno Fantin

    La Revue Du Praticien
    |June 14, 2014
    PubMed
    Summary

    Surgical site infections (SSIs) are a significant risk in orthopaedic surgery, impacting patients undergoing arthroplasty and fracture fixation. Prompt diagnosis and multidisciplinary management, including surgery and targeted antibiotics, are crucial for successful treatment outcomes.

    Area of Science:

    • Orthopaedic Surgery
    • Infectious Diseases
    • Microbiology

    Context:

    • Surgical site infections (SSIs) are a major complication in instrumented orthopaedic surgery, with incidence rates varying from 0.5–2% after arthroplasty to 30% after open fracture fixation.
    • Infections can be acute (early or late) or delayed, caused by different pathogens (e.g., Staphylococcus aureus, coagulase-negative staphylococci) and presenting with diverse clinical signs.
    • Delayed infections, often subtle and challenging to diagnose, require advanced imaging and microbiological analysis.

    Purpose:

    • To outline the epidemiology, classification, and diagnostic challenges of surgical site infections in orthopaedic implant procedures.
    • To emphasize the critical role of interdisciplinary collaboration among surgeons, microbiologists, and infectious disease specialists in managing these complex infections.
    • To detail the treatment strategies, including surgical interventions and antimicrobial therapy, based on pathogen characteristics and patient factors.

    More Related Videos

    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
    10:35

    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

    Published on: December 3, 2017

    12.6K
    In Vivo Mouse Model of Spinal Implant Infection
    08:03

    In Vivo Mouse Model of Spinal Implant Infection

    Published on: June 23, 2020

    2.5K

    Related Experiment Videos

    Last Updated: Apr 28, 2026

    Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
    04:37

    Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

    Published on: February 2, 2024

    1.4K
    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
    10:35

    Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

    Published on: December 3, 2017

    12.6K
    In Vivo Mouse Model of Spinal Implant Infection
    08:03

    In Vivo Mouse Model of Spinal Implant Infection

    Published on: June 23, 2020

    2.5K

    Summary:

    • SSIs are a significant complication in orthopaedic surgery, with varying incidence and causative organisms.
    • Diagnosis of delayed infections can be difficult, necessitating advanced imaging and fluid cultures.
    • Management requires a multidisciplinary approach, combining surgical intervention with prolonged, targeted antibiotic therapy.
    • Treatment success rates, guided by current protocols, range from 60% to 80%.

    Impact:

    • Improved understanding of SSI pathogenesis and clinical presentation in orthopaedic patients.
    • Highlights the necessity of a collaborative, evidence-based approach for optimizing patient outcomes.
    • Provides a framework for selecting appropriate surgical and antimicrobial strategies, potentially reducing morbidity and improving cure rates.