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Updated: Apr 28, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
[Application of ozonated perftoran in the treatment of spreaded peritonitis]
Abstract:
Results of surgical treatment of 114 patients, suffering spreaded peritonitis of various etkoogy, were analyzed. To patients of the comparison group basic conservative therapy was conducted. In patients of the main group was applied intravenous infusion of ozonated perftoran (OP) in 1 mg/kg dose, concentration of ozone 5 mg/l, solely or together with metabolic immunomodulator and detoxicator glutoxim. To all the patients the routine clinical investigations were conducted: in the blood erythrocytes there were measured concentration of diane conjugates, of malonic dialdehyde, activity of catalase, content of the middle molecular mass peptides in blood and urine, as well as of rest nitrogen, urea, creatinine, common bilirubin, state of the protein and electrolyte balance. Basing on analysis of results of the conducted investigations there was revealed, that combined, local and systematic, application of OP and glutoxim together with basic therapy in spreaded peritonitis is pathogenetically substantiated.
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