Related Experiment Video
Updated: Aug 9, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
Published on: September 14, 2014
Elevated soluble CD8 levels in sera of human immunodeficiency virus-infected populations
M M Reddy1, M Lange, M H Grieco
1R. A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital Center, New York, New York 10019.
Abstract:
Soluble CD8 levels in sera were quantitated in asymptomatic intravenous drug abusers, homosexuals, and patients with lymphadenopathy or acquired immunodeficiency syndrome. Soluble CD8 levels were elevated in human immunodeficiency virus-seronegative intravenous drug abusers and homosexuals, probably reflecting infections like cytomegalovirus. The sera of human immunodeficiency virus-seropositive groups of patients with human immunodeficiency virus infection also had elevated levels of soluble CD8, reflecting infections like cytomegalovirus and human immunodeficiency virus infection.
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