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Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
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Susceptibility-weighted imaging in pediatric neuroimaging.

Thangamadhan Bosemani1, Andrea Poretti, Thierry A G M Huisman

  • 1Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Journal of Magnetic Resonance Imaging : JMRI
|June 14, 2014
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Summary

Susceptibility-weighted imaging (SWI) is crucial for pediatric neuroimaging, aiding in diagnosing conditions by detecting abnormalities and using blood oxygen level dependent venography. This review highlights SWI's expanding role in pediatric brain pathology diagnosis and understanding.

Keywords:
childrenneuroimagingsusceptibility-weighted imaging

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Area of Science:

  • Radiology
  • Neuroimaging
  • Pediatric Medicine

Background:

  • Susceptibility-weighted imaging (SWI) is an essential magnetic resonance (MR) sequence in pediatric neuroimaging.
  • Its application has seen significant recent expansion.
  • SWI detects hemorrhage, calcium, and nonheme iron via susceptibility artifacts.

Purpose of the Study:

  • To provide a comprehensive review of SWI utility in pediatric neuroimaging.
  • To discuss SWI's role in diagnosis and differential diagnosis of pediatric brain pathologies.
  • To explore SWI's contribution to understanding the pathomechanisms of these conditions.

Main Methods:

  • Review of existing literature and case studies on SWI in pediatric neuroimaging.
  • Analysis of SWI's capabilities in identifying various neuroimaging biomarkers.
  • Discussion of the blood oxygen level dependent (BOLD) venography principle utilized by SWI.

Main Results:

  • SWI effectively identifies hemorrhage, calcium, and iron deposits.
  • The BOLD venography principle enables earlier diagnosis of several pediatric neurological diseases.
  • SWI aids in establishing diagnoses and differential diagnoses for pediatric brain pathologies.

Conclusions:

  • SWI is a powerful tool in pediatric neuroimaging with expanding applications.
  • Its ability to detect susceptibility artifacts and utilize BOLD venography is key to its diagnostic utility.
  • SWI is instrumental in diagnosing, differentiating, and understanding the pathomechanisms of pediatric brain conditions.