Related Experiment Video
Updated: Apr 28, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
Published on: April 7, 2023
Decreased motor function is associated with poorer cognitive function in elderly with type 2 diabetes
Elizabeth Guerrero-Berroa1, Ramit Ravona-Springer2, Anthony Heymann3
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA.
Background/Aims:
Impaired motor function has been associated with cognitive impairment and dementia, but this relationship is poorly understood in elderly with type 2 diabetes (T2D). We thus investigated it in a large sample (n = 726) of cognitively normal elderly with T2D.
Methods:
In this cross-sectional study, hierarchical linear regressions assessed correlations of 3 motor measures (timed walk, grip strength, and self-reported motor difficulties) with episodic memory, attention/working memory, semantic categorization, executive function, and overall cognition controlling for demographics.
Results:
Longer timed walk and weaker grip strength were associated with poorer performance in all cognitive domains except episodic memory.
Conclusions:
Associations of motor and cognitive functions in T2D and non-T2D samples are consistent. A lack of association of motor function with episodic memory may suggest non-Alzheimer's disease-related underlying mechanisms.
More Related Videos
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
05:39A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
Published on: June 13, 2025
Related Concept Videos
Type II Diabetes II: Pathophysiology
Diabetic Neuropathy
Alzheimer Disease l: Introduction
Type I Diabetes II: Pathophysiology
Type I Diabetes III: Clinical Manifestations
Psychoneuroimmunology: Diabetes and Cancer