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Updated: Apr 28, 2026

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Sarcoidosis--the greatest mimic.
Varut Vardhanabhuti1, Chun-Lap Pang1, Tishi Ninan1
1Department of Radiology, Derriford Hospital, Plymouth, Devon, UK.
Seminars in Ultrasound, CT, and MR
|June 16, 2014
Summary
Sarcoidosis affects multiple organs and mimics other diseases due to nonspecific symptoms. This review uses imaging in real cases to show systemic sarcoidosis manifestations.
Area of Science:
- Internal Medicine
- Radiology
- Pathology
Background:
- Sarcoidosis pathogenesis remains largely unknown.
- It is a multisystem inflammatory disease.
- Clinical presentation and imaging are often nonspecific, mimicking other conditions.
Observation:
- Diagnosis relies on clinical suspicion.
- Imaging is vital for detection and monitoring.
- This review uses a case-based approach with real clinical encounters.
Findings:
- The review details various systemic manifestations of sarcoidosis.
- Diverse imaging modalities are employed to visualize disease impact.
- Case studies illustrate the diagnostic challenges and imaging utility.
Implications:
- Highlights the importance of imaging in diagnosing and managing sarcoidosis.
- Provides a practical, case-based guide for clinicians.
- Enhances understanding of sarcoidosis's diverse systemic presentations.
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