Related Experiment Video
Updated: Apr 28, 2026

07:12
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
4.7K
Parathyroid conditions in childhood
Jocelyn F Burke1, Herbert Chen2, Ankush Gosain3
1Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, Wisconsin 53792.
Seminars in Pediatric Surgery
|June 17, 2014
Summary
This review covers pediatric hyperparathyroidism (HPT), a rare condition involving parathyroid hormone overproduction. It details HPT
Area of Science:
- Pediatric Endocrinology
- Surgical Oncology
- Genetics
Background:
- Hyperparathyroidism (HPT) is rare in children, affecting 2-5 per 100,000.
- Management principles are often adapted from adult cases.
- Unique pediatric considerations are crucial for effective care.
Purpose of the Study:
- To review parathyroid surgery in pediatric patients.
- To highlight the pathophysiology, clinical presentation, and treatment of HPT in children.
- To address pediatric-specific aspects of parathyroid disease and surgery.
Main Methods:
- Literature review focusing on pediatric hyperparathyroidism.
- Analysis of embryology, anatomy, and pathophysiology.
- Examination of clinical presentation, imaging, and surgical approaches.
Main Results:
- HPT in children necessitates specialized care due to its rarity.
- Surgical treatment requires consideration of unique pediatric factors.
- Understanding presentation, imaging, and operative techniques is key.
Conclusions:
- Pediatric hyperparathyroidism requires tailored management strategies.
- Surgical interventions must account for growth and development.
- Further research into pediatric-specific HPT is warranted.
More Related Videos
Related Concept Videos
The Parathyroid Glands
5.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
5.2K
Adrenal Gland Disorders
3.7K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.7K
Hypothyroidism II: Pathophysiology
20
Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
20
Hyperthyroidism II: Pathophysiology
26
Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH...
26
Graves Disease II: Pathophysiology
20
Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor,...
20
Bone Disorders
8.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.0K

