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Updated: Apr 28, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Idiopathic Seidlmayer's Purpura: A Case Report
Maria Cristina Maggio1, Fabrizia Ferraro1, Saveria Sabrina Ragusa1
1Department Pro.S.A.M.I., Ospedale dei Bambini 'G. Di Cristina', ARNAS Palermo, Palermo, Italy.
Abstract:
Acute hemorrhagic edema of infancy (AHEI) was considered a rare form of Henoch-Schönlein purpura; however, it is now regarded as an independent disease typically involving patients aged 4-24 months. The authors describe the clinical case of a toddler aged 8 months, with skin erythematous pomphoid lesions, treated at home with topical steroids without benefits. The appearance of new lesions and the worsening of the previous skin signs induced the parents to drive the child to the hospital. The medical history revealed the administration of a vaccine dose 2 months before.
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