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Related Concept Videos

Thermoregulation01:26

Thermoregulation

2.9K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
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Assessing Body Temperature - Axilla01:14

Assessing Body Temperature - Axilla

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Procedural Guide for Assessing Axillary Body Temperature using a Digital Thermometer:
Step 1: Perform hand hygiene and put on clean gloves to maintain infection control and prevent cross-contamination.
Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
Step 3: Adjust the patient’s clothing to expose only the axilla. It minimizes...
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Body Temperature01:25

Body Temperature

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The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
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Body Temperature01:07

Body Temperature

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Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
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Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

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Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
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Thermosensation01:43

Thermosensation

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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Related Experiment Video

Updated: Apr 28, 2026

Measuring Skeletal Muscle Thermogenesis in Mice and Rats
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Measuring Skeletal Muscle Thermogenesis in Mice and Rats

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Does intramuscular thermal feedback modulate eccrine sweating in exercising humans?

G Todd1, C J Gordon, H Groeller

  • 1Centre for Human and Applied Physiology, School of Medicine, University of Wollongong, Wollongong, NSW, Australia.

Acta Physiologica (Oxford, England)
|June 18, 2014
PubMed
Summary
This summary is machine-generated.

Skeletal muscles may contain thermosensitive elements influencing sweat secretion. Intramuscular temperature changes showed a faster link to sweating than deep-body temperature, suggesting a role in thermoregulation.

Keywords:
core temperatureexercisemuscle temperaturesweatingthermoregulation

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Area of Science:

  • Exercise physiology
  • Thermoregulation
  • Human physiology

Background:

  • Skeletal muscles' potential role in thermoregulation is understudied.
  • Understanding the interplay between muscle temperature and sweating is crucial for exercise science.

Purpose of the Study:

  • To investigate the temporal relationship between dynamic changes in deep-body and intramuscular temperatures and eccrine sweat secretion.
  • To explore the possibility of thermosensitive elements within skeletal muscles modulating thermoeffector responses.

Main Methods:

  • Eight subjects performed cycling with sinusoidal workload variations.
  • Oesophageal, mean skin, and intramuscular (vastus lateralis) temperatures were measured.
  • Temperatures were cross-correlated with forehead sweat rates.

Main Results:

  • Both intramuscular and oesophageal temperatures strongly correlated with sweating variations.
  • The phase delay between intramuscular temperature and sweating was significantly shorter than for oesophageal temperature.
  • Maximal cross-correlation coefficients for intramuscular and oesophageal temperatures were not significantly different.

Conclusions:

  • Temporal coupling of sweating to intramuscular temperature supports the presence of muscle thermosensitive elements.
  • Skeletal muscles appear to play a role in modulating thermal sweating responses.
  • Findings advance understanding of the physiological mechanisms of thermoregulation during exercise.